The Jennifer Brown Research Laboratory was established at the University of Edinburgh / MRC Centre for Reproductive Health by PiggyBankKids (now Theirworld) in 2004.
The laboratory is home to a team of world class scientists and clinicians working with a unified focus and commitment to solving unanswered questions in perinatal medicine.
Complications of pregnancy such as preterm birth, poor fetal growth, and certain maternal medical disorders are closely associated with abnormal brain development in the offspring. Disturbances to brain development can lead to significant long-term problems for survivors and their families, and prevent affected children from fulfilling their education and employment potentials.
Children born at less than 37 weeks of gestation each year
Globally, fifteen million children are born at less than 37 weeks’ of gestation each year and this number is rising. Preterm birth is the single biggest cause of death and disability among newborn babies and it is a leading cause of neurodevelopmental impairment in childhood.
Improved understanding of the disturbances to brain structure and function that accompany preterm birth, and other complications of pregnancy, is essential for the development of therapies designed to improve outcome.
To improve the lives of women and children who suffer complications in pregnancy and the newborn period
A major strength of our research projects is the unified focus on obstetric and neonatal problems. We study mouse models of preterm labour, brain injury and inflammation, and we use state-of-the-art magnetic resonance imaging (MRI) techniques to uncover the effects of perinatal adversity on brain development in fetal and neonatal life.